A study of 228,876 pregnancies, published in the July issue of the American journal of Obstetrics & Gynecology, finds that maternal antidepressant use is associated with shortened (4-5 days) gestational age; for each prescription filled in the second trimester, the risk of early labor doubled.  In the third trimester, antidepressant use was associated with an elevated risk of infant convulsions.

Abstract → 

Hayes, R., Wu, P., et al; “Maternal antidepressant use and adverse outcomes: a cohort study of 228,876 pregnancies,” American Journal of Obstetrics & Gynecology Vol. 207(1) 49.e`-49.e9, July 2012

Related Item:
More questions on antidepressants during pregnancy