Six men were hospitalized and one was pronounced brain dead after participating in a phase 1 clinical drug for a mood, anxiety, and motor dysfunction drug manufactured by Bial and administered by Biotrial. Carl Elliott, a bioethicist at the University of Minnesota, said investigators should look into questions like how much the men were paid and whether they properly consented to the trial. “Many Phase 1 trial volunteers are poor and unemployed, and they volunteer for trials like this because they are desperate for money,” he said. “This means they are easily exploited.”
An international group of researchers from multiple disciplines has published a historical, qualitative, and quantitative investigation into voice-hearing in women. The interdisciplinary project, freely available from Frontiers in Psychiatry, explores how sexism, exploitation, and oppression bear on women’s experiences of hearing voices.
Talk therapy has long been associated with symptom and behavioral changes, but new research shows that it may also lead to neural changes in the brain. The recently published research found that transference-focused psychotherapy (TFP) was linked to alterations in neural circuitry in women diagnosed with borderline personality disorder (BPD).
“Offenders sentenced to forensic psychiatric care do not consider their 'mental illness' to be the main reason for their crime. Instead, they point to abuse, poverty or anger toward a particular person.”
A former pharma executive has broken ranks with the industry in a new book by reporting how multiple psychiatrists, schools, and his desperate hopes pressed him to allow higher and higher doses of antipsychotic medications. The result: his 15-year-old son’s death from Seroquel.
In this month’s Schizophrenia Bulletin, a person diagnosed with autism, OCD, obsessive-compulsive personality disorder, and major depressive disorder provides a first-hand close reading and description of their own psychiatric experiences.
Researchers recently completed a first of its kind, large-scale international survey of attitudes about mental health and they were surprised by the results. According to their analysis published in this month’s issue of the Journal of Affective Disorders, people in developed countries, like the United States, are more likely to assume that ‘mental illnesses’ are similar to physical illnesses and biological or genetic in origin, but they are also much less likely to think that individuals can overcome these challenges and make a full recovery.
New research published in the August issue of Psychiatric Annals evaluates the results of randomized control trials on the use of various psychotropic drugs for patients diagnosed with borderline personality disorder (BPD). Despite the “American Psychiatric Association’s practice guidelines endorsement of SSRIs as first-line therapies for BPD,” the results of the meta-analysis reveal that pharmacotherapy in BPD is “not supported by the current literature,” and “should be avoided whenever possible.”
Willingness to interact with someone with a mental health diagnosis may be tied to the misperception that disorders can be transferred from one person to another, according to a new study published in the Journal of Memory & Cognition. More →
Psychiatrists are giving drugs to most people with emotionally unstable personality disorders outside of the best-practice clinical guidelines, according to a study in the Journal of Clinical Psychiatry. And an accompanying editorial stated that the reason is because "therapy takes time." More →
To help my non-recovery oriented colleagues understand the stigma/resentment associated with ‘borderline personality disorder,’ I simply mention this: “Let’s say I call you and say, ‘Hey, I’ve got a referral for you. She’s been diagnosed with borderline personality disorder . . .’” I need to go no further; without fail, my colleague will smile or laugh. We both know that such a referral is a no-no, so much so that it doesn’t even have to be mentioned; it is a given.
Based on my experience both as a therapist and client in the mental health field, I have learned that when therapists or psychiatrists give you the following diagnoses all too often here is what they really mean:
My name is Leah Harris and I’m a survivor. I am a survivor of psychiatric abuse and trauma. My parents died largely as a result of terrible psychiatric practice. Psychiatric practice that took them when they were young adults and struggling with experiences they didn’t understand. Experiences that were labeled as schizophrenia. Bipolar disorder. My parents were turned from people into permanent patients. They suffered the indignities of forced treatment. Seclusion and restraint. Forced electroshock. Involuntary outpatient commitment. And a shocking amount of disabling heavy-duty psychiatric drugs. And they died young, from a combination of the toxic effects of overmedication, and broken spirits.
A review of the literature from 2001 to 2011 on child abuse, neglect, and psychiatric disorders finds that early life stress subtypes can predict the development of psychopathology subtypes in adults. Physical & sexual abuse and unspecified neglect were associated with mood & anxiety disorders. Emotional abuse was associated with personality disorders and schizophrenia, and physical neglect with personality disorders. The research appears in the December issue of the Journal of Nervous and Mental Disease.
This blog was prompted by an invitation to do a guest post on the site of one of my favorite bloggers, 1 Boring Old Man. This is my response to the notion that there are certain conditions – Schizophrenia among them – that correspond more directly to biomedical conditions
I think it is time to reclaim the word disability. Disability needs to be appreciated. To the extent we value community over isolation, anything anyone cannot do, or needs help with, builds community. There are infinite examples in every career and walk of life of how necessary “disability” (since we’re calling it that) is for connection, service and meaning in life. Without it we’d have absolutely no need for each other. And the fastest way to despair is to feel unnecessary.
A prospective study in the American Journal of Psychiatry compares Dialectical Behavior Therapy (DBT) with psychiatric management for borderline personality disorder, founding that outcomes after two years were equivalent for both groups. Both groups exhibited poor functional outcome after 36 months (53% neither employed or in school, 39% receiving disability). However, an editorial in the same issue reports that clinicians over-react to the immediate clinical presentations of borderline, but that the long-term outcomes are positive nonetheless.
“Mixed anxiety-depressive disorder,” “attenuated psychosis syndrome,” “obsessive-compulsive personality disorder,” “antisocial personality disorder,” and “nonsuicidal self-injury” were among diagnoses that met with disappointing results in field trials for the new DSM-5. Either low interrater reliability (a lack of sufficient agreement between …
Researchers from Australia and the UK found that people with a schizophrenia diagnosis almost four times more likely than controls to have a history of childhood adversity. The quality of the evidence in this meta-analysis of the currently available data was found to be very strong (p<0.00001). No difference in rates of childhood adversity were found between schizophrenia and affective psychosis, depression, and personality disorders. Rates of childhood adversity is slightly higher in dissociative disorders and PTSD. Results will appear in Psychological Medicine.
Researchers in Australia investigate the growing evidence that childhood trauma predisposes individuals to both bipolar and borderline syndromes, with the intention of examining areas of discrimination between the diagnoses. "No studies have examined the neurobiological underpinnings of both in the same design," they say, and research comparing bipolar and borderline patients' self-reports is limited. This paper provides an overview of emotional dysregulation, impulsivity, childhood environment and neurobiology in the context of bipolar and borderline diagnoses. The authors conclude with the question of whether the two belong to the same spectrum. The paper will appear in Australian and New Zealand Journal of Psychiatry.
Article Abstract: Although research supports the stigma and labeling perspective, empirical evidence also indicates that a social safety net remains intact for those with mental illness, recalling the classic “sick role” concept. Here, insights from social networks theory are offered …
Multimillionaire U.K. psychiatrist Dr. George Hibbert is being investigated - potentially by Parliament - for deliberately misdiagnosing hundreds of parents with 'personality disorders' in order to fit the view of the social service agency for whom he worked that their children should be taken away. The lawyer for one of the parents said "we believe this may be the tip of a very big iceberg."
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