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Two facts about Robert Califf are beyond question. He is an expert on clinical trials, who is already seen as a leading architect of the future of medical research. And as the New York Times put it, he has “deeper ties to the pharmaceutical industry than any FDA commissioner in recent memory”. A lot of senior figures in medicine support Califf in spite of his ties to Pharma. The guy is just so bright, and understands the nuts and bolts of drug research so well! Surely a person like this is more useful than some outsider who offers only a squeaky-clean resume, they argue.

Before the early 1990’s the use of antipsychotic medications was largely reserved for adults with severe psychotic disorders; unpleasant involuntary movement disorders (extrapyramidal side-effects) and cardiovascular risks appear to have largely limited their use outside these disorders. The introduction and intense marketing of what seemed to be better tolerated and safer (now proven not to be), second generation atypical antipsychotics (AAPs) such as risperidone, olanzapine, quetiapine, ziprasidone and aripiprazole from the mid 1990’s led to a rapid expansion of antipsychotic medication use for a wide variety of unlicensed conditions and in more diverse clinical populations.

I face the daily challenge at my urban center in Hartford, Connecticut of working with young adults (18-25) coming out of the juvenile system into adult outpatient care. Most of these youngsters come to us on multiple medications of all classes. Almost all have stories of trauma, abuse and neglect going back some generations. Almost all carry psychiatric labels of bipolar or schizoaffective or personality or behavioral disorders. Very few of them have ever been told of the long-term effects of the medications they have been prescribed.

In the late 1990’s, the NIMH set out to provide the most extensive review ever conducted of the effectiveness of ADHD medications in children. It was known as the Multisite Multimodal Treatment Study of Children with ADHD (MTA study). In 1999, NIMH announced that after 14 months, well-constructed medication management programs provided better results than other treatments, including behavioral therapy. But the study was not over, and the tables started to turn. By the end of three years, medication not only provided no more benefits over other options, it actually predicted greater deterioration of symptoms.

“And so what we should be thinking about is our responsibility to care for and shield them from harm and give them the...

You never know what you’re going to accomplish when you start something. Who could have predicted that Tom Insel and NIMH would throw the APA and the DSM under the bus? My guess is that two factors played a big part in NIMH’s decision. First, the unceasing barrage of criticism directed at the DSM – its lack of construct validity; its declining inter-rater reliability – had damaged its credibility beyond repair. On top of that, thirty years of DSM-based research had produced no biomarkers.

If we accept Robert Whitaker and Lisa Cosgrove’s assessment that informed consent for a person to participate in psychiatry is not informed consent because of the fraud that Americans are subjected to by organized psychiatry, then the consensus for laws that support forced psychiatry have also not been garnered with informed consent. If the average person is offering support to psychiatry via their legislators, because they are operating under the fraud organized psychiatry has perpetrated on the people, then that support is illegitimate.

Grainne was courageous to do this interview: I was struck by her strong love for John and her very deep sensitivity to the violence she has witnessed him undergo in the name of treatment. Let us all lend our hearts and passion to the international campaign to free John Hunt and to ensure that no one ever has to suffer the abuses he has suffered.

My story is no doubt unlike the others you will hear. I tell a story of justice denied in the United States, which has the possibility of being redressed if the CRPD is ratified and fully implemented - without being encumbered by reservations or by declarations and understandings amounting to reservations. It is also a story of the awakening of hope in the world - led this time by other countries, not the United States - for a future we can all be proud of.

People who are considered the highest functioning in American culture such as politicians, lawyers, medical doctors (including psychiatrists), major league sport players, etc., all lack certain abilities that I possess (and, of course, vice-versa). Are their abilities actually the real ones and mine “soft,” surreal, abstract, inaccessible and useless? In order to redefine health, we must redefine worth. Are you sure the “abled” are able to accomplish what you value? Are you sure the “disabled” aren't more able to heal the world?

Hearing distressing voices is highly correlated with traumatic experiences, and many people report that their first experience with distressing voices occurs after a trauma....

I remember looking out of my living room window, drawing on my connection to all the women in the world who had felt this energy before, all that were in that moment, and all that would in time to come. This energy, this incredible power, was like a wave that I was riding for a brief window of my life, and sharing with my baby to move us through time into a new type of union. To me, this wasn’t anything to resist, to be afraid of, or to suppress. All I had to do was be there to witness, and keep my mind from getting in the way.

There is a class of “naturalistic” research that can only be conducted if the researcher happens to be in the “right” place at the “right” time. Julia Rucklidge was running clinical trials using micronutrients to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in adults when major earthquakes hit New Zealand. She and her research team contacted all current and past participants to establish whether they were taking micronutrients and for how long, and then they assessed how anxious, depressed and stressed people were one and two weeks post-quake. The results were revealing.

Twenty-five years before Prozac, 1 in 10,000 of us per year was admitted for severe depressive disorder - melancholia. Today at any one point in time 1 in 10 of us are supposedly depressed and between 1 in 2 and 1 in 5 of us will be depressed over a lifetime. Around 1 in 10 pregnant women are on an antidepressant.

I am committed. Fully committed to creating a solution. Are you with me? I think medications and labels for people experiencing emotional distress should be almost entirely eliminated, and should not be applied first, for everyone and forever, to people experiencing extreme states. Our current mental health system is a permanent solution to a temporary problem. We need mental health exit ramps, we need human ways to help each other in crisis and through adversity, we need compassion and love and friendship in times of struggle. We need each other.

So here we go again; another meeting with another young person who describes how he is in an acute crisis - you may call it - and is diagnosed and prescribed neuroleptics. He is told by the doctor that he suffers from a life-long illness and he will from now on be dependent on his “medication.” As long as people are met this way I see no alternative than showing that there are alternatives. If that means being "antipsychiatry," then I am more than happy to define myself and our work in that way.

Dutch investigators will soon publish an article in Neurochemistry International that sheds light on how SSRI antidepressants affect the serotonergic system over the longer...

In Paris today we have a lot of people mouthing words that come easily: "Je Suis Charlie." For anyone who wants to be Charlie, who wants to get to know what modern politics is all about, by feeling it in your marrow, try reporting an adverse event on treatment to your doctor. Outside your doctor’s surgery/clinic/ consultation room you can believe you are operating in a democracy. Inside the room you may be treated with courtesy and apparent friendliness but you are being treated in an arrangement set in place to police addicts. This is not a domain in which ideals of Liberty, Equality or Fraternity are welcome.

On November 12, 2013, Molecular Psychiatry published online Evidence That Duplications of 22q11.2 Protect Against Schizophrenia, by Rees et al. The print version was published last month – January 2014. The idea of a genetic mutation that would protect one from schizophrenia aroused a good deal of interest and enthusiasm. The paper has added some impetus to psychiatry's claim that the condition known as schizophrenia is a genetic disease. For this reason, I thought it might be helpful to take a closer look at the study.

On May 16, 2014, I retired from a 35-year career as a professor of clinical psychology at Miami University. As a part of my retirement celebration, I gave a Final Lecture to my Department. These Final Lectures give retiring faculty members the opportunity to talk about anything they think is important for their colleagues and the attending students to hear. I focused on the changes I have witnessed in the profession of clinical psychology over my career; changes that were not for the better.

The Massachusetts Benzo Bill H4062: Informed consent for benzodiazepines and non-benzodiazepine hypnotics was just scheduled to be heard by the Joint Committee on Mental Health and Substance Abuse on Monday, April 4th. Less than a week away! The committee will decide whether the bill moves forward to the house and senate, goes to study, or is denied.

This post and the ones to follow will summarize my current thinking on the optimal use of neuroleptic drugs.

With nothing left to lose, I’d reached the point at which I had to make a choice: to fight, or to give up. Though things seemed to not be going my way, I decided to take back control and make drastic changes in hopes to survive. That’s when yoga, meditation and nutrition came into my life, but first, I had to find a doctor to help me get off the medication I was currently on.

Today, July 1, 2016, the Alaska Supreme Court issued its Opinion in In the Matter of the Hospitalization of Mark V.    What strikes me the most about the case is that Mark's expressing the view that a psychiatric drug he was being required to take is poison, that it had side effects related to his sexual performance, and that it was killing him were all cited as proving Mark was delusional. As readers of this site know, these drugs can quite reasonably be characterized as poison, they do cause sexual dysfunction, and they are quite lethal to many many people, shortening lives on average by 25 years for those in the public mental health system, such as Mark.

Since I left the psychiatric prescribing trenches and came south for the winter, I’ve been staying in a beach town within driving distance of a technology metropolis. I take breaks from my writing and walk to the beach. There, I meet and talk with the winners of the American dream. They are intelligent, highly educated and financially successful. They take their beach vacations here.