Researchers Warn of “Brain Atrophy” in Children Prescribed Antipsychotics

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Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.

Systematic Review Finds Antidepressant Withdrawal Common and Potentially Long-lasting

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Prominent researchers conduct a review of antidepressant withdrawal incidence, duration, and severity. Results lead to call for new clinical guidelines.

How Western Psychiatry Harms Alternative Understandings of Mental Health

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An anthropological look at the Global Mental Health (GMH) movement suggests several ethical problems and contradictions in its mission.

Poor Evidence and Substantial Bias in Ritalin Studies

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The authors of a large scale well-conducted systematic review of methylphenidate, also known as Ritalin, conclude that there is a lack of quality evidence for the drug’s effectiveness. Their research also revealed that Ritalin can cause sleep problems and decreased appetite in children.

Antidepressant Use Does Not Prevent Suicide, Study Finds

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A new study has found that antidepressants are ineffective for reducing suicide attempts. Researchers report that the risk of suicide is particularly high in the first month after starting an antidepressant.

Brain Response to Antidepressant Mirrors Placebo Effect

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People diagnosed with severe depression show the same changes in brain scans when they respond to a placebo as they do when they take an actual antidepressant, according to a new study. Researchers also found that those whose symptoms were decreased by a placebo were more likely to report relief from antidepressant drugs.

Danish Study Finds Better 10-year Outcomes in Patients Off Antipsychotics

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Study finds that 74% of patients with a psychotic disorder off antipsychotics at end of 10 years are in remission.

Review Explores First-Person Experiences of People Taking Antipsychotics

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A new systematic review finds that patients report reduced symptoms but also loss of self and agency while taking antipsychotics.

Reanalysis of STAR*D Study Suggests Overestimation of Antidepressant Efficacy

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Reanalysis of the original primary outcome measure in the STAR*D study suggests STAR*D findings inflate improvement on antidepressant medication and exclusion criteria in conventional clinical trials results in overestimation of antidepressant efficacy.

Largest Survey of Antipsychotic Experiences Reveals Negative Results

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A new survey exploring antipsychotic user experience finds that more than half of the participants report only negative experiences.

German Psychologists Declare “the Drugs Don’t Work”

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JĂĽrgen Margraf and Silvia Schneider, both well-known psychologists at the University of Bochum in Germany, claim that psychotropic drugs are no solution to mental...

Better Outcomes Off Medication for Those Recovered from First-Episode Schizophrenia

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A new study has found that of 10 people who were fully recovered from their first episode of schizophrenia (FES), those not taking antipsychotics did better in terms of cognitive, social, and role functioning—and reached full recovery more quickly.

Initial Trial of Ayahuasca for Depression Shows Promising Results

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Ayahuasca found to be effective in treating moderate to severe depression in low-income population.

Publication Bias Inflates Perceived Efficacy of Depression Treatments, Study Finds

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Researchers report the cumulative effects of major biases on the apparent efficacy of antidepressant and psychotherapy treatments.

SNRIs Added to the List of Drugs with Potential Withdrawal Symptoms

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New research suggests that clinicians should exercise caution prescribing SNRIs as first-line treatment for mood and anxiety disorders.

Benzodiazepine Use Linked to Dementia and Memory Loss

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A recent review of the research found that benzodiazepine use may have long-term effects on memory and increase the risk for dementia. The study,...

Valproate Linked to Decreased Brain Volume in Children Diagnosed with Bipolar Disorder

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Researchers find that valproate decreases brain volume in a region associated with emotion processing across all participants.

Psychologist Rethinks Psychotropic Medications, Calls for Renewed Dialogue

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Psychologist and Professor Amber Gum has published the story of her personal journey of rethinking psychotropic medication in a special issue on "The Politics of Mental Health" in The Journal of Medicine and the Person. Influenced by Mad in America and the work of Robert Whitaker, Gum became aware of evidence that “suggests that psychotropic medications are less effective and more harmful than most believe” and now hopes to encourage other mental health professionals and researchers to engage in open-minded, critical self-assessment of standard practices.

Researchers Find Bias in Industry-Funded Continuing Medical Education

Industry-funded continuing medical education (CME) influences physicians to prescribe more opioids, focus less on the consequences.

Rethinking Madness and Medication: Researcher Discusses Psychiatric Drug Withdrawal and Survivor Movements

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New understandings of medication and withdrawal experiences warrant rethinking conceptualizations of health and “madness."

PTSD and Psychiatric Medication Linked to Dementia in Older Veterans

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Veterans diagnosed with PTSD and taking SSRIs, novel antidepressants, or atypical antipsychotics are more likely to develop dementia.

Long-term Usage of ADHD Drugs Linked to Growth Suppression

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Findings suggest that treatment not only fails to reduce the severity of “ADHD” symptoms in adulthood but is associated with decreased height.

Does Longer Duration of Untreated Psychosis Cause Worse Outcomes?

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New research counters the long-held assumption that a longer duration of untreated psychosis is associated with worse outcomes.

New Study Casts Doubt on Efficacy of Ketamine for Depression

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A new study, published this month in the Journal of Affective Disorders, investigated the effectiveness of weekly intravenous ketamine injections as a treatment for...

Light Therapy Outperforms Prozac for Depression

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In a new study, researchers found that bright light therapy was an effective treatment for nonseasonal major depressive disorder (MDD) while Prozac (Fluoxetine) alone...