Benzodiazepines Linked to Treatment Resistant Depression
Prior use of benzodiazepines, such as Xanax, Librium, or Ativan, may increase the risk of treatment-resistant depression (TRD), according to a new study published in The Journal of Nervous and Mental Disease.
Citizens Petition Calls for Sexual Side Effect Warnings
Researchers take action after study exposes enduring sexual dysfunction as a potential side effect of serotonin reuptake inhibiting antidepressants, 5α-reductase inhibitors, and isotretinoin.
Antidepressants Linked to Dementia
A study published in this month’s issue of the Journal of Clinical Psychiatry found that the use of antidepressant drugs was associated with an...
Suicide Warning on Antidepressant Label is Justified, Researchers Say
Researchers confirm that the suicide warning for antidepressants is justified by the evidence and that claims that the warning is harmful lack support.
ADHD Drugs Linked to Psychotic Symptoms in Children
Stimulant medications like Ritalin and Adderall, often prescribed to treat children diagnosed with ADHD, are known to cause hallucinations and psychotic symptoms. Until recently these adverse effects were considered to be rare. A new study to be published in the January issue of Pediatrics challenges this belief, however, and finds that many more children may be experiencing psychotic symptoms as a result of these drugs than previously acknowledged.
Poor Evidence and Substantial Bias in Ritalin Studies
The authors of a large scale well-conducted systematic review of methylphenidate, also known as Ritalin, conclude that there is a lack of quality evidence for the drug’s effectiveness. Their research also revealed that Ritalin can cause sleep problems and decreased appetite in children.
Antipsychotic Trials Show Increasing Placebo Response and Declining Drug Response
A new review of antipsychotic trials conducted over the last 24 years finds that the placebo response rate is steadily increasing, and drug response is decreasing.
More Children Receiving ‘Off-Label’ Antipsychotics for ‘ADHD’
Over the past twenty years, the number of prescriptions for atypical antipsychotics written to children and young adults between four and eighteen has increased...
After the Black-Box: Majority of Children Starting SSRIs Still Receiving Too High of Dose
In 2004, the FDA added a black-box warning to SSRI antidepressants on the increased risk of suicide among children taking these drugs. A new study suggests that this warning has increased the proportion of children who begin an antidepressant on a low dose, but the majority are still receiving higher than recommended doses.
Industry Funded Trials Favor Drugs Over Psychotherapy
The researchers conclude that industry funding appears to bias studies towards pharmacotherapy over psychotherapy for the treatment of depression.
Ketamine for Harmful Drinking: A Look at the Data
New research contends that ketamine can reduce problematic alcohol use but does the data support the claims?
‘Do Antidepressants Work?’ is the Wrong Question
“This research points to the inadequacy of asking the simple question: ‘Do antidepressants work?’ Instead, the value or otherwise of antidepressants needs to be understood in the context of the diversity of experience and the particular meaning they hold in people’s lives.”
Study Examines the Difficulty of Withdrawing from Antidepressant Drugs
Correcting unnecessary long-term antidepressant use is difficult and met with apprehension by providers and service-users.
Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies
Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.
Study Links SSRIs to Violent Crime in Youth
Individuals between the ages of 15 and 24 are more likely to commit a violent crime if they are taking an SSRI antidepressant than if they are not, according to new research out of Sweden. The study published in PLoS Medicine on Tuesday, suggests "warnings about the increased risk of violent behavior among young people taking SSRIs might be needed.”
New Study Finds Brain Changes in Newborns Exposed to Antidepressants
A fist of its kind neuroscience study, published this month in Cerebral Cortex, found changes in the brain electrical activity of infants exposed to SSRI antidepressants during pregnancy.
Patients With Schizophrenia Show Better Work Functioning Off Antipsychotics
20-year follow-up study finds that after four years, patients not prescribed antipsychotics have significantly better work functioning.
Safety Analysis Weighs Harms and Benefits of Antipsychotic Drugs
The researchers find that the drug effects for reducing psychosis are small and that treatment failure and severe side effects are common.
Experts Decry Dangerous Use of Antipsychotics in Children
In a featured article for Psychiatric Services, psychiatrists from Dartmouth raise the alarm on the increasing numbers of children prescribed dangerous antipsychotic drugs. Despite the fact that data on the safety of long-term use of these drugs in this vulnerable population “do not exist,” the rate of children and adolescents being prescribed antipsychotic drugs have continued to increase over the past fifteen years.
Hypnotic Medications Linked to Suicide Risk
A recent review found that hypnotic medications are associated with risks of suicide and suicidal ideation.
STOP or GO? Tapering Pregnant Women off of Antidepressants
A team in the Netherlands is currently investigating the effects of tapering off of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) during pregnancy....
Clinical Trials Show Antidepressants “Not Beneficial in the Long Term”
Clinical trials also consistently fail to measure and report long-term harmful effects.
New Research on Prenatal SSRI Exposure and Autism
Does maternal SSRI exposure increase the chances that a child will develop characteristics associated with Autism Spectrum Disorder (ASD)?
Exposure to Antidepressants in the Womb Linked to Autism
Researchers, publishing in Toxicology Research, review the evidence that antidepressant exposure in the womb is linked to autism spectrum disorders (ASD) in humans.
Psychotherapy Effectiveness for Depression Inflated by Publication Bias
While publication bias has been known to overestimate the efficacy of antidepressant treatments, a new study suggests that research on the use of psychotherapy in depression suffers from a similar bias.
