Antidepressant Use and Cognitive Impairment After Menopause

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A study of 6,998 postmenopausal women followed over 7.5 years found that antidepressant use correlated with a 70% increased risk of cognitive impairment. The...

Study of Antidepressants and Suicide is Retracted

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A controversial 2010 paper, "Antidepressant Medication Prevents Suicide in Depression", has been retracted by Acta Psychiatrica Scandinavica. In a contemporaneous issue of British Journal of...

Children’s Positive Responses to Antidepressants “Minimal” After Four Weeks

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Children's positive responses to SSRI antidepressant treatments for depression are even less significant than adult responses, and do not last beyond four weeks.

Increased Risk of Heart Defects with SSRIs

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Danish research found a significantly increased risk of congenital heart defects in both the 4,183 pregnancies exposed to SSRIs throughout the first trimester and the...

Bereaved Parents Prescribed Meds Quickly, Stay on Meds Long-Term

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MiA blogger Jeffrey Lacasse's study of psychiatric prescribing in response to perinatal/neonatal death (co-authored with Joanne Cacciatore) finds that 37% of participants in an...

Antidepressants Increase Suicide Risk in Children and Adolescents

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In a meta-analysis of studies of 6039 individuals, researchers in the UK determined that, consistent with previous meta-analysses, antidepressants increased "suicide-related outcomes."  Read more    ...

Therapy Better than Antidepressants for Staying Employed

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Examining the link between depression and loss of employment, a study by American researchers in the British Journal of Psychiatry found that cognitive therapy...

Zoloft Causes Cells to Eat Themselves

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Researchers at Princeton found that Zoloft accumulates in yeast cells, leading to curvature of the cellular membrane that triggers "autophagy," wherein cells eat themselves...

Antidepressants and Advertising: Psychopharmaceuticals in Crisis

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An article by written by faculty of the Harvard History of Science Department and the Program in Placebo Studies explores how "drug marketing portrays...

Quality of Relationship to Doctor Significantly Improves Antidepressant Efficacy

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The more that patients feel that they have a high-quality relationship with their prescribing physician, the more likely that they will regard their own responses to antidepressants as positive.

Brain Volume Recovers With Remission, Not With Medication

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In a prospective study of 28 outpatients with major depression, Canadian researchers investigated whether brain volume changes stabilized with antidepressant treatment and/or reversed with...

Antidepressant Use Associated With Menstruation Disorders

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In a study of 793 women taking antidepressants and 639 not taking them, researchers in Turkey found that menstruation disorders were significantly associated with...

Bipolar Patients Have High Drug Burden — Especially Women

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Over one third of people with bipolar diagnoses admitted to a Rhode Island hospital were on four or more psychiatric medications, says research published...

Prescription Drugs May Cause One Third of All Birth Defects

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Up to a third of all birth defects may be linked to prescription drugs, according to a review of the evidence published in The...

Prenatal Exposure to SSRIs Significantly Increases Autism & Developmental Delays

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Research on 966 mother-child pairs from the Childhood Autism Risks from Genetics and the Environment (CHARGE) Study finds that prenatal SSRI exposure was nearly 3...

Antidepressant is Toxic to Fungus

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Zoloft isn't just for depression any more; it also kills fungal meningitis. Researchers from Texas A&M find that "The problem for many current antifungal...

2X Risk of Postpartum Hemorrhage Antidepressants

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A study of 106,000 pregnant women with a diagnosis of mood or anxiety disorder, by researchers from Harvard, Duke, Michigan State and the university...

Discontinuing Psychotropics Reduces Falls in Elderly

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Australian researchers look at the literature on the effect of psychotropics on falls in the elderly; largest effect of any randomized trial was achieved...

Antidepressants Have No Effect On Bipolar Depression

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In a review of 68 articles published between 2005 and 2011, Israeli researchers found that most well-controlled studies failed to show a significant effect of...

Suicide Attempts Similar With Various Antidepressants for Children

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Researchers from Vanderbilt University and the University of Alabama found, in a retrospective study of increased suicidal behavior among 36,842 children who were new...

Cumulative Risk of Impairment and Death From Anticholinergic Medication

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The New York Times reports that a two-year longitudinal study of over 13,000 men and women over 65 found that anticholinergic medications, which include many...

Fish Exposed to Prozac Exhibit Significantly Altered Behavior

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Concentrations of Prozac as low as 1 microgram per liter (Οg/L), a concentration that has been found in many freshwater environments, were found to significantly...

Genetic Markers do not Predict Response to Antidepressants

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Researchers from 11 nations in Europe and North America find, in the largest study to date of possible links between genetic markers and antidepressant...

Antidepressants Linked to Risk of Adult-Onset Diabetes

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A meta-analysis of studies of 168,435 adults who were free of diabetes at baseline found that those who used antidepressant medication were 68% more...

Majority of Anorexia Patients are Prescribed Psychotropics Despite Lack of Data

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Research from the medical schools of Harvard University and the University of Melbourne, reported in the December International Journal of Eating Disorders, found that...