Antidepressants

For those with severe depression, inpatient CBT was effective but the adding antidepressants did not improve treatment outcomes.

Recent claims about antidepressant effectiveness have been based on misleading statements and misunderstandings of the science.

A new study suggests that taking antidepressants impairs empathy, while the experience of depression itself does not.

In a study of 630 elderly Manhattanites without dementia, researchers from the Netherlands found that antidepressant use was associated with significantly more brain atrophy,...

I’m alive. More than 30,000 veterans in the past decade alone are not. I was not warned of the risks of this drug. I was not told that once on it, I might never be able to get off it, or the nightmare that would ensue when I tried. I know millions of others were not told either.

Greater cumulative doses of drugs that are anticholinergic or block the neurotransmitter acetylcholine are associated with significant increases in dementia and Alzheimer's.

Nearly 90,000 American adults are going to emergency rooms every year in response to adverse events from psychiatric medications, according to a study in...

The addition of fluoxetine to CBT did not further reduce depressive symptoms in young people with moderate-to-severe depression.

A Molecular Psychiatry study found that people who had recurrent depression developed smaller hippocampi and antidepressants protected against that effect -- except insofar as the study evidence seemed to show the opposite of what the media reported on it.

The U.S. Department of Health and Human Services’ Agency for Healthcare Research and Quality has released a meta-analysis “Evidence Report” of the studies into...

The use of antidepressants has risen quickly among older adults but the rate of depressive symptoms in this population has not declined as a result.

According to patient reports, SSRI antidepressants most frequently lead to the subjective experience of emotional blunting.

Taking an SSRI antidepressant was associated with a 26% increased risk of violent crime conviction.

Use of antidepressants increased the risk of organ-specific malformations in women with depression

Researchers from Samaritan Mental Health in Corvallis, Oregon successfully treated 12 patients for anxiety by discontinuing their antidepressant medications. Some received alternative medications for...

A new study looks at how online communities provide information and support for patients experiencing psychiatric drug withdrawal.

A new study investigates how antidepressant withdrawal effects often get confounded with depression relapse in clinical trials.

In a prospective cohort study of 466 pregnant women over 10 years, researchers at the California Teratogen Information Service found that women exposed to...

The initial study, which has been used to promote antidepressants, employed outcome switching to hide poor results.

A study in Urology found that men receiving Zoloft for treatment of premature ejaculation had a significant reduction in sperm concentration and significant increase...

Noted antidepressant researcher, Michael Hengartner, summarizes the latest research on the use of antidepressants in children and adolescents.

Four different studies conducted in different ways examining different groups have linked use of certain psychiatric drugs to bone fracture risks and negative impacts on human bone development.

Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

Pregnant women taking antidepressant medications, especially during the second trimester, have an increased risk of preeclampsia, a potentially serious or even fatal condition.

Researchers suggest that because most antidepressant “success” is due to the placebo effect, they may never find a way to predict outcomes.