There was a drug being tested for tardive dyskinesia called Kinecta a couple of years ago. Psychiatry web sites were flooded with patient-recruitment ads. I remember some fancy foot work involving changing end points in mid-trial to create the impression that it worked. As I recall, the ads didn’t mention TD. They just wanted people on antipsychotics. The atypical and abnormally awful Ability is a champion at causing akathisia, which is also classed When test as an add-on to antidepressant treatment in depression, 25% of subjects were afflicted. FDA said that was just fine and approved it.as extra-pyramidal, like TD. Agitation or maybe Akathisa is mentioned on the patient insert as a possible side effect, but if at least 25% of those who use it are going to experience hell, a box warning is required in my opinion.