Do you really have to go through a period of detoxification? I thought you could just slowly work your way up to about 1,000-2,000 mg of niacin. I have the book Orthomolecular Treatment for Schizophrenia and I thought you just take the recommended doses of 1-2 grams per meal. Also, I am in Milwaukee, could you email me the info for Dr. Fox? My email is [email protected] thanks!!!!