Science News: Psychiatric Drugs

An expert looks through research papers with a magnifying glass

When Medical Science Refuses to Correct Itself

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Science is supposed to be self-correcting. But what happens when the journals entrusted to uphold this principle become its gatekeepers?

Benzodiazepine Use Tied to Increased Risk of Death, Especially at Higher Doses

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Benzodiazepine use is common, with research estimating as many as 12.6% of US adults report past-year use. A 2019 study found significant increases in...

“Assault” and “Torture”: Patients Recall the Institutional Violence of Forced Drugging

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A new article published in the Journal of Humanistic Psychology finds that patients often experience forced drugging in psychiatric contexts as dehumanizing and violent....

“Every Time I Took a Pill, I Felt I Was No Longer Myself”: Young...

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A new study published online by the Journal of Humanistic Psychology examines young adults’ experience of taking and discontinuing antipsychotic drugs after completing a...

Antidepressants Linked to Suicide Risk, Irregular Heartbeat, and Sudden Death

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This week Mad in America examines three studies related to adverse effects of antidepressants. The first study finds that antidepressant use is linked to...

New Research Links Psychotropic Drugs to Heart and Pancreatic Risks While Keto Diet Shows...

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This week Mad in America examines three studies related to the adverse effects of psychotropic drugs and one that investigates the effect of keto...

Questioning the Prescription: Antidepressants and the Medicalization of Childhood

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This week Mad in America explores four recently published articles related to antidepressant use in children and adolescents. The first reports that although clinical...

Weekly Research Digest: Psych Drugs Linked to Poor Heart Health and Gastrointestinal Bleeding

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This week Mad in America examines studies related to adverse events associated with antipsychotics and antidepressants, including two studies that found increased risk of...

Harm for Profit: Are Nursing Homes Drugging Residents to Avoid Paying for Adequate Staffing?

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Long-term care facilities commonly prescribe antipsychotic drugs to elderly service users, often to treat behavioral issues associated with dementia. Despite a lack of evidence...

Weekly Research Digest: Bullying, Social Media, and SSRI’s Link to Suicide

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This week, Mad in America examines research around increased suicide risk in children and adolescents related to bullying in high-school and the use of...

Weekly Research Digest: Bad Research, Unsupported Beliefs, and Sleep Apnea

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This week, Mad in America examines recent antidepressant research questioning withdrawal severity, a study of unsupported biological beliefs about mental "illness," and research linking...
Young man supporting his friend in depression

Anti-inflammatory Drugs Fail for Depression

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Response and remission rates failed to beat placebo in a new Harvard meta-analysis, throwing the inflammation hypothesis into question.
Miniature people - The worker at work with medicine pills

Antidepressant “Maintenance Treatment” Not Required: Slow Tapering with Support Works

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Questions remain about best practices for discontinuation strategies, and the distinction between relapse and withdrawal was not defined.

Medication-Free Treatment in Norway Found Effective Over the Short Term

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Those who received drug-tapering support did just as well or better than those receiving treatment as usual.
older adult hands close-up, wheelchair

Psych Drugs Linked to Increased Risk of ALS

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Psychiatric drugs linked to increased risk of the rare, incurable neurological disease that causes loss of motor function.

Easier to Refill Than Review: Antidepressant Prescribing in Primary Care

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Researchers found that for many doctors, renewing antidepressant prescriptions feels safer and faster than helping people taper, and that most current interventions fail to address the pressures driving that choice.

Commentary: Does First Year Treatment With an Antipsychotic Lead to Long-Term Harm?

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There is no good evidence that antipsychotics provide a benefit to first-episode or early-episode psychotic patients.

New Evidence in Support of Tapering Protocols for First-Episode Psychosis

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The study shows that tapering can be successfully and relatively safely done by most people after first-episode psychosis.

“Medicine Is Awesome” Mentality Fueling Harmful Antidepressant Use, Say Experts

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The authors call for a paradigm shift in mental health care that emphasizes empathy, context, and alternatives to medication as first-line treatments for depression.

German GPs Say They Need More Support to Help Patients Stop Antidepressants

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New research from Germany shows how guidelines, system pressures, and lack of collaboration limit deprescribing.