Saturday, December 3, 2022

Science News: Psychiatric Drugs

Gradual Tapering Recommended for Antidepressant Discontinuation

6
A new literature review reinforces the need to “down-titrate” or taper antidepressants, especially drugs like Celexa and Paxil.

Lithium Use Leads to Chronic Kidney Disease

7
New evidence suggests that lithium, commonly prescribed for bipolar disorder, can increase the risk of chronic kidney disease.

Antidepressant Withdrawal Linked to Suicide Attempt in Case Study

0
Researchers suggest that antidepressant withdrawal can be a possible precipitant of suicide.

Long Term Antidepressant Use Associated With Increased Morbidity and Mortality

0
A study finds that commonly prescribed antidepressants are associated with the development of diabetes, hypertension, and other diseases.
Illustration of a shape of a baby crawling made out of various types of pills, on a black background

Health Risks to Babies When Antidepressants Used During Pregnancy

4
Babies born to mothers taking antidepressants during pregnancy were more than six times as likely to have neonatal withdrawal syndrome—including breathing problems, irritability/agitation, tremors, feeding problems, and seizures—than those born to mothers taking other types of drugs.

Antidepressants No Better Than Placebo for About 85% of People

25
Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

Less Than a Quarter of Those with Depression Respond to Treatment in Real Life

70
In a real-world setting, less than a quarter of patients diagnosed with depression improved with medication, hospitalization, and therapy.

Psychiatric Drugs Do Not Improve Disease or Reduce Mortality

54
Nassir Ghaemi: “Most psychiatric medications are purely symptomatic, with no known or proven effect on the underlying disease. They are like 50 variations of aspirin, used for fever or headache, rather than drugs that treat the causes of fever or headache.”
Man closely examing instructions on prescription medications

Antidepressant-Induced Serotonin Syndrome a Danger for the Elderly

1
Researchers found that 25% of elderly patients taking antidepressants had serotonin syndrome, which is potentially life-threatening.

Industry Corruption in Systematic Review for Injectable Antipsychotics

1
Researchers highlight how systematic reviews are compromised by pharmaceutical industry ties by exposing a study of injectable antipsychotics.

Stimulants Don’t Improve Academic Performance in Kids with ADHD

6
“Efforts to improve learning in children with ADHD should focus on obtaining effective academic instruction rather than stimulant medication.”
Scowling teenage boy holding up pills sealed in blister packs in his hand as he leans on a wooden table with an intense stare

Risk of Depression Spikes When Kids Take Ritalin

1
Risk of depression increased when children were taking methylphenidate for ADHD, but once they stopped taking the drug, depression risk dropped to normal levels.

Research Explores the Experience of Benzodiazepine Withdrawal

7
A new study reveals many benzodiazepine users are misinformed about the risks of withdrawal and experience devastating consequences.

How to Distinguish Antidepressant Withdrawal from Relapse

5
Mark Horowitz and David Taylor provide advice on how to tell the difference between antidepressant withdrawal and depression relapse.

Did Psychiatry Ever Endorse the Chemical Imbalance Theory of Depression?

26
With the chemical imbalance theory falling out of fashion, researchers examine the claim that psychiatry never truly endorsed it.
Image of a young girl looking at a handful of antidepressants.

Antidepressants Do Not Improve Quality of Life

13
A new study found that taking antidepressants did not improve quality of life.
Bored young man, staring out the train window on a rainy, grey and dull day

Patient Reports Reveal SSRI Antidepressants Often Lead to Emotional Blunting

7
According to patient reports, SSRI antidepressants most frequently lead to the subjective experience of emotional blunting.

Many Service Users Interested in Decreasing Antipsychotic Use with Professional Help

8
New research examines service user attitudes on discontinuing and reducing antipsychotic drugs.

Antipsychotics Often Prescribed Without Informed Consent

25
New research reveals that patients are often not given fully informed consent before being prescribed antipsychotics.

Antipsychotics Worsen Cognitive Functioning in First-Episode Psychosis

1
Withholding antipsychotics may be beneficial for memory, the researchers write.

rxisk

Rxisk maintains a searchable database of adverse effects of prescription drugs that have been reported to the FDA in the United States, Health Canada, and to RxISK.