Saturday, September 25, 2021

Science News: Psychiatric Drugs

Antipsychotics Increase Risk of Dementia; New Research Illuminates Why

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In JAMA psychiatry, researchers outline new theories connecting antipsychotic use in people with schizophrenia and increased dementia risk.

Newborn Babies Go Through Antidepressant Withdrawal

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A new study finds that newborn babies experience antidepressant withdrawal after birth if their mothers take SSRIs when pregnant.

Psychiatric Drugs may Reduce Social and Emotional Capacities

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Research finds that social cognition and emotional processing abilities can be disrupted by psychiatric drugs.

Tapered Antipsychotic Withdrawal Mitigates Risk of Psychotic Symptoms

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Research suggests that slowly tapering off an antipsychotic reduces the risk of withdrawal psychosis compared to abrupt discontinuation.

“Relapse” in Antidepressant Trials Likely Caused by Sudden Withdrawal

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A new study investigates how antidepressant withdrawal effects often get confounded with depression relapse in clinical trials.

Sudden Antipsychotic Withdrawal—Not Low Dose—Leads to Relapse

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A new article in Lancet Psychiatry debunks past studies claiming that those on low doses of antipsychotics are more likely to relapse.

Antipsychotic Adherence Research Overlooks Key Information

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Researchers argue for a shift away from a focus on antipsychotic adherence toward understanding service users’ diverse patterns of use.
Question mark inside a maze in the shape of human head.

New Study: The Clinical High Risk for Psychosis (CHR-P) Model Is Flawed

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The CHR-P model focuses on “attenuated psychosis” to predict “transition” to schizophrenia and ignores other factors. But new research shows that the model is a poor predictor.

Researchers Propose Study to Test Whether Antidepressants Impede Recovery

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Evolutionary theorists suggest that antidepressants interfere with the adaptive function of depression and propose a test of this theory.

Four Essential Studies on Antidepressant Withdrawal Every Prescriber Must Read

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A researcher and service user Stevie Lewis recounts her own experience with antidepressant withdrawal and what she wishes her doctors knew.
Doctor and patient

Barriers to Shared Decision Making in the Prescription of Antipsychotics

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Researchers push for a renewed focus on true shared decision-making for patients diagnosed with psychosis.

No, the FDA’s Black Box Warning Did not Increase Suicides

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Researchers again debunk the claim that the FDA black box warnings on antidepressants led to more suicides.

Psychotherapy Can Prevent Relapse When Discontinuing Antidepressants

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“Short and simple psychological programs can prevent people from relapsing when they stop their antidepressants.”

Allen Frances Takes on the Over-Prescription of Antidepressants

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The prominent psychiatrist explores why antidepressants remain highly overprescribed and offers solutions to the problem.

Anticholinergic Medications Linked to Cognitive Impairment in Schizophrenia

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Researchers have found further evidence that the anticholinergic effect of psychiatric drugs can lead to cognitive impairments.

Ethical Issues Raised Over FDA Collaboration with Biogen on Failed Drug

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The FDA collaborated with Biogen to conduct repeated re-analyses of aducanumab for Alzheimer's and FDA committee members are raising concerns.

Study Confirms Overdiagnosis of ADHD in Children and Teens

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Medical researchers present evidence that ADHD is overdiagnosed in children and teens, which can lead to significant harm.

Antidepressants Not Clinically Useful for Back Pain

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While professional guidelines recommend antidepressants for back pain, researchers point out the lack of evidence for their usefulness.

Cochrane Review Calls for More Research on Antidepressant Withdrawal

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Researchers find a lack of current literature on safe, effective ways to manage antidepressant withdrawal and make suggestions for future research.

Stimulant Prescribing Patterns for ADHD Not Impacted by Scientific Evidence

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The article suggests that research challenging the evidence for ADHD drugs does not lead to changes without public campaigns.

rxisk

Rxisk maintains a searchable database of adverse effects of prescription drugs that have been reported to the FDA in the United States, Health Canada, and to RxISK.