Sunday, August 14, 2022

Science News: Psychiatric Drugs

Less Than a Quarter of Those with Depression Respond to Treatment in Real Life

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In a real-world setting, less than a quarter of patients diagnosed with depression improved with medication, hospitalization, and therapy.

Psychiatric Drugs Do Not Improve Disease or Reduce Mortality

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Nassir Ghaemi: “Most psychiatric medications are purely symptomatic, with no known or proven effect on the underlying disease. They are like 50 variations of aspirin, used for fever or headache, rather than drugs that treat the causes of fever or headache.”
Man closely examing instructions on prescription medications

Antidepressant-Induced Serotonin Syndrome a Danger for the Elderly

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Researchers found that 25% of elderly patients taking antidepressants had serotonin syndrome, which is potentially life-threatening.

Industry Corruption in Systematic Review for Injectable Antipsychotics

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Researchers highlight how systematic reviews are compromised by pharmaceutical industry ties by exposing a study of injectable antipsychotics.

Stimulants Don’t Improve Academic Performance in Kids with ADHD

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“Efforts to improve learning in children with ADHD should focus on obtaining effective academic instruction rather than stimulant medication.”
Scowling teenage boy holding up pills sealed in blister packs in his hand as he leans on a wooden table with an intense stare

Risk of Depression Spikes When Kids Take Ritalin

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Risk of depression increased when children were taking methylphenidate for ADHD, but once they stopped taking the drug, depression risk dropped to normal levels.

Research Explores the Experience of Benzodiazepine Withdrawal

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A new study reveals many benzodiazepine users are misinformed about the risks of withdrawal and experience devastating consequences.

How to Distinguish Antidepressant Withdrawal from Relapse

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Mark Horowitz and David Taylor provide advice on how to tell the difference between antidepressant withdrawal and depression relapse.

Did Psychiatry Ever Endorse the Chemical Imbalance Theory of Depression?

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With the chemical imbalance theory falling out of fashion, researchers examine the claim that psychiatry never truly endorsed it.
Image of a young girl looking at a handful of antidepressants.

Antidepressants Do Not Improve Quality of Life

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A new study found that taking antidepressants did not improve quality of life.
Bored young man, staring out the train window on a rainy, grey and dull day

Patient Reports Reveal SSRI Antidepressants Often Lead to Emotional Blunting

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According to patient reports, SSRI antidepressants most frequently lead to the subjective experience of emotional blunting.

Many Service Users Interested in Decreasing Antipsychotic Use with Professional Help

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New research examines service user attitudes on discontinuing and reducing antipsychotic drugs.

Antipsychotics Often Prescribed Without Informed Consent

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New research reveals that patients are often not given fully informed consent before being prescribed antipsychotics.

Antipsychotics Worsen Cognitive Functioning in First-Episode Psychosis

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Withholding antipsychotics may be beneficial for memory, the researchers write.
Girl, looking confused, holding pill bottle

Official Guidelines on Antidepressant Discontinuation Fail Practitioners and Patients

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A review of clinical practice guidelines for antidepressant discontinuation from across the English-speaking world reveals major pitfalls.

Medicating Preschoolers for ADHD: How “Evidence-Based” Psychiatry Has Led to a Tragic End

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The prescribing of stimulants to preschoolers diagnosed with ADHD is on the rise, which is said to be an "evidence-based" practice. A review of that "evidence base" reveals that claims that ADHD is characterized by genetic and brain abnormalities are belied by the data, and that the NIMH trial of methylphenidate in this age group told of long-term harm.
Depression related documents and drugs

Shifting Away from ECT and Antidepressants for Depression

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Researchers argue that we need a paradigm shift away from the biomedical model of mental illness to one informed by political action and common sense.

Negative Antidepressant Trials Still Unlikely to Be Published

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Antidepressant trials with negative results are still more likely than not to either be misleadingly spun as positive or unpublished.
Doctor attentively examines the MRI scan of the patient.

SSRI Antidepressants Do Not Improve Depression After a Stroke

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A study in JAMA Neurology finds that antidepressants do not reduce depression symptoms more than placebo in patients recovering from a stroke.
guy holding pill

New Review: Antidepressants Come with Minimal Benefits, Several Risks

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A review of research on antidepressant efficacy finds that an unfavorable risk-to-benefit ratio.

rxisk

Rxisk maintains a searchable database of adverse effects of prescription drugs that have been reported to the FDA in the United States, Health Canada, and to RxISK.