I have been diagnosed with major depression, social anxiety, generalized anxiety, and OCD. When I read these articles rarely do they mention spectrum disorders, or any reference is vague. To say someone has major depression, suggests they only have one issue, and not several that fall on a scale, or a spectrum. So when I took Zoloft for the first time at age thirty-five it allowed me to enjoy reading, and I could read a book from start to finish for the first time. I also developed quit a sense of humour, as the depression symptoms lifted. The disadvantage was I started to put on weight.