Thanks for the link. I stand with my previous comments as it is unclear to me how data on the treatment relates to the results. It seems that the baseline data is already treated patients in which case they demonstrate only that the more depressed people are, the more treatment they recieve. You certainly cannot conclude much with regard to treatment effects. The author states: At best, treatment was insufficient to overcome liabilities among persons with MDD in the current sample. That is true, however a negatively biased conclusion. Second he concludes: Moreover, treat- ment including medication may have worsened depression. This could be technically true as “may have” allows for wide intrepretation, but given the huge selection bias it is not fair. Unlike the headline the report in itself is not rigorous, but should be better explained, so that it is much more clear what we really can learn from the data – and much less what is the authors idea/opinion on the matter. These issues are really complicated, so adhering to what data says is paramount, not adhering to our own opinion!