Hey, Thanks for the reply. Dr. Hoffer did give Niacin to people on antipsychotics as well. Infact, he very slowly keeps reducing the dose of antispychotics to keep them to a minimum or completely take them off it. He postulated that Schizophrenics are “Niacin Dependent” – meaning they will need Niacin intake for life just like anticpsychotics, but Niacin wont produce such drastic and negative side effects that Antipsychotics has.. Hoffer noticed that people who started Niacin treatment within one year of their Schizphrenia Onset were most like to recover (90%). That number keeps coming down as time passes by and depends on the intake of antipsychotics as well. If you dont mind me asking, How old is your son ? When was he diagnosed and when did he start taking the medicines ? Which meds and what dosages is he on right now ? Hoffer noticed that it may sometimes take 5-10 years for patients to ‘recover’ on Niacin….