A big problem I have with studies of anti-depressants – other than the obvious damage it does to the brains of the people involved – is that every person reacts differently to each anti-depressant. That much was proven to me with the first anti-depressant I ever used – Prozac. The first time I used it, the weight of the world was lifted off my shoulders. I lost my job and so could not afford to continue using it. When I finally got back on it, NOTHING happened! No relief At All! In fact, I never experienced that relief ever again – over nearly 30 years on anti-depressants. I weaned off them this year.