I tried to read all the comments, but I had to stop at “KnowledgeIsPower” and the claim that you are “getting the facts out there”. There are some facts mixed with opinion and very dangerous ignorance. It is my opinion that anyone making policy or stating publicly their opinion on pain, should have firsthand knowledge first. No, your little back pain incident doesn’t count. I do agree with you that these are common occurrences that do not call for opiates. So, let’s go through the article. We are taught about addictive nature because we have used scientific observation on humans, not rats. According to Dr. Dana Smith, “We believe there are three crucial traits that comprise much of the risk of developing a dependency on drugs: sensation-seeking, impulsivity and compulsivity…We can test for these traits using standard questionnaires, or with cognitive-behavioral tests, which can also be administered in an fMRI scanner to get an idea of what is going on in the brain behaviorally.” So, your conclusion is that man can elicit and control it. Do you have personal experience with this? Have you ever tried an addictive substance? I have tried many and not gotten addicted. One example is alcohol. My mother was an alcoholic. I used to drink casually. Now, I don’t at all. Next, you posit that “light bulbs likely went on in many entrepreneurs’ minds about the huge, as-yet untapped market”. In 1954? Really? We’re talking about drugs here. The way I understand it, discoveries are made, then entrepreneurs go crazy, so it makes no sense that Walmart would decide to make Xanax (or whatever it was then) based on a rat study, especially in 1954. I would think that a proper scientist would back up his theory with a proper example. You’re talking about feel-good drugs here, so what does antibiotics have to do with it? You just threw that out there. I’m not going to try to debate your expertise on our need for antidepressants, but I would like to point out that you give a reason for their popularity and reference a footnote #2 that gives a different reason. America was dealing with PTSD after so much war. Diet aids are different, though. Now we’re getting back into medical stuff, and your point seems to be that if it’s addictive, it’s a scam. Losing weight can save someone’s life. Addiction is a carefully weighed risk against that. If someone weighs over 450 lbs. for example, the risk would be worth it. I don’t call that a scam. The next point would be a good one, if you were a medical expert and this were an article making a medical point. Diabetes, cholesterol, hypertension and ulcer care are certainly making the medical community rich, when diet and exercise could avoid a pill, but Americans would rather have their fast food, so I’m not sure I would blame the doctors here. But then you lead into withdrawal, which makes no sense. We’ve gone back into your territory and you need to list off the drugs that actually involve withdrawal, not those associated with the above paragraph. In the next paragraph you starkly contradict yourself! If, as you say, man is in control and can elicit our addiction, how can you then say “people, unlike rats, were thinking ahead and opting to avoid their addictive rewards”? Now to believe your next point, we’d all have to be conspiracy theorists, but it is important to refute it anyway and I’ll say why in my conclusion, but to believe that all the doctors, or even a large number of them, got together and planned this is a bit ridiculous. Lucky for them the addictive drugs just happened to work for the problems you describe. Huge coincidence. Yes, everyone feels anxiety, but as I noted in another post, you imply that everyone is at the same level of anxiety by what you are saying. A bit of anxiety over a first date is different than getting chest pains, feeling so weak you collapse, losing your ability to speak or think clearly…all over having to call the water department. You should not be commenting on physical pain. This is a mental health site, and I think you have demonstrated that you don’t understand physical pain. It is not in your wheelhouse. I do agree with you, however, that CPS and Fibromyalgia were invented…to justify the doctors not being able to find an answer. They’ve done it to me out of laziness. Even though I have underlying causes, they’ve still given me those silly diagnoses. I also have a list of 25 other problems. My pain reaches 10 on a daily basis. I also agree that opioids are overprescribed, but now because of people like you, we are going in the opposite direction, and pain is not being treated at all. Pain Management doctors created this problem. Before my back surgery I was on Oxycontin, Hydrocodone, Soma AND Xanax! Of course, I didn’t take it all. As you said, people know better, but I quit that doctor eventually as well, because I realized he was part of the problem. This was way back in 1999. I then went for 5 years with no pain pills and it was hell. I disagree with how you characterize addiction, but it is silly to treat an opioid with an opioid. I have gone through all this trouble to refute your arguments, because this has been taken too far. It was taken too far the moment the CDC Regulations came out, but we had no warning for that, so now we must find a way to have them changed. I’m sure I won’t change your mind, but hopefully others will read this, because people are dying. This is not hyperbole. https://www.painnewsnetwork.org/stories/2017/9/4/how-chronic-pain-killed-my-husband http://nationalpainreport.com/chronic-pain-a-suicide-story-8835614.html http://www.lynnwebstermd.com/suicide-and-chronic-pain/ The government, and our doctors, have made suicide a viable option for pain relief…not an impulsive, sad, I can’t take it anymore action, but a planned viable option. This needs to change. I don’t want to add that option to my list. When will that be? I honestly don’t know.