Both liquid tapering and tapering by crushed tablets are unreliable. To create the most precise dosage; which is very important especially with the smallest doses, you need custom made tablets, produced with the initial Active Pharmaceutical Ingredient. I had an interview with the director of the Dutch professional association of pharmacists and he emphasized that titrate medication with liqiuds is a very uncertain way of tapering. You never know for sure how much medication is in a certain amount of liquid. The heap of crushed tablets contain a very small part of the active ingredient and many excipients it is impossible to come up with equally dosed portions. GSK already says in a report on paroxetine (seroxat) for EMA in 2005 that ‘smaller dosages are neccessary to make a safe withdrawal possible’.