Just about Folic acid: last year i assumed as part of a therapy suggested by an orthomolecular doctor 2,5 mg of folic acid x day. I must admit i felt a good mood for the first weeks but right 1 week after i began this supplements i got a flu that lasted for 5 and half monthes. Tried to stop everything one by one without success after it turned out my flu was without any apparent cause. Just after i stopped folic acid (wich casually i kept for last) the flu ceased in a pair of weeks. I have read that folic acid is believed by some to create problems on conversion to 5-mthf. As i am a1298cMTHFR homozigous maybe this could be an explanation for my bad experience. That’s just to say something about folic acid.