I have severe social anxiety and social avoidance behavior. I was given Seroquel XR 100 mg ( a low dose) and it helped my mind but I gained a lot of weight on it and I couldn’t take the weight off no matter what I did (while I was on the drug). The psych nurse told me that a low dose of Seroquel likely won’t give me any problems with weight gain. Later I was transferred to another psychiatrist and he told me to get off the Seroquel XR b/c even a low dose will likely cause weight gain and increased risk for diabetes. I’m obese as it is, so that last thing I need to do is gain weight. It’s a shame that most of the psychiatric drugs cause weight gain. I’m sure many people take them without problems or major side effects, but that’s not the case for me.