p.s. re: “If you have scientific evidence that demonstrates how your simple game can effectively treat these gravely suffering patients and halt or reverse the damage to their brains and cognitive functioning, that would be wonderful. So far, my brief search for such evidence did not produce any such results.” The game is new and there is no literature on it yet, although it’s probably in the category of “behavioral activation,” which has been studied. It has been used for about 20 depression patients at the Brigham and Women’s hospital in Boston and has been successfully used by quite a few people on-line. It is a promising area for scientific study, I believe, but this is a little different than DBS. There is clearly no risk to trying this. It is and fast acting and even fun to do. If you are a depressed person, you might as well just try it and see if it works. There is nothing to lose by trying.