Researchers at Harvard University, in the largest and most detailed study on the topic to date, found that childhood maltreatment is significantly associated with reduced hippocampal volumes. Reduced hippocampal volumes have been implicated with chronic and first-episode schizophrenia, depression, dissociative identity disorder, borderline personality disorder, and bipolar disorder. This is the first study to demonstrate that the condition is associated with childhood maltreatment irrespective of diagnosis. The results were published today in Proceedings of the National Academy of Sciences.
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