Negative Symptoms Have a Greater Impact Than Positive Symptoms

An analysis of the NIMH CATIE trial shows that negative symptoms have a greater impact on functioning, quality of life, and outcomes than positive symptoms in schizophrenia. This analysis was motivated by a recognition of functioning, rather than the management of positive symptoms, as a target of treatment. The analysis was published in Schizophrenia Research.
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Mad in America hosts blogs by a diverse group of writers. These posts are designed to serve as a public forum for a discussion—broadly speaking—of psychiatry and its treatments. The opinions expressed are the writers’ own.