Antipsychotic Polypharmacy Commonly Prescribed Ahead of Guidelines

In one day at a psychiatric hospital in Vitoria-Gasteiz, Spain, of the 201 patients admitted 172 were prescribed antipsychotic drugs and 47% of those were prescribed more than one. Researchers found that four of the most common two-drug combinations had no supporting clinical evidence, and that there was no supporting evidence for any of the three-drug combinations. 12 patients were prescribed combinations with known negative interactions. Results of the study are in the March issue of General Hospital Psychiatry.

Article →


Mad in America hosts blogs by a diverse group of writers. These posts are designed to serve as a public forum for a discussion—broadly speaking—of psychiatry and its treatments. The opinions expressed are the writers’ own.