Sensitivity to Threatening Faces Predicts Depression

Researchers in China found that among 27 young adults with early-onset major depressive disorder matched against 25 healthy controls, MRI detected elevated response in the left amygdala, thalamus, prefrontal and temporal cortex and significantly lower response in the right prefrontal cortex in response to threat-related facial expressions. This response was significantly correlated with depression. Results are published in this month’s Psychiatry Research.

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