The Cure May Be Worse Than the Disease

Maintenance Antipsychotic Therapy.  Cole, J. American Journal of Psychiatry, 132 (1977): 32-6.

In 1977, Jonathan Cole, the former head of the NIMH Psychopharmacology Service Center, concluded that given the myriad of problems caused by antipsychotic medications, “every chronic schizophrenic outpatient maintained on an antipsychotic medication should have the benefit of an adequate trial without drugs.” He titled his article “Is the Cure Worse than the Disease?”

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