National Institute of Health: Antipsychotics “Provide Suboptimal Response At Best”


A National Institute of Health review of treatment strategies for early onset schizophrenia that will appear in Frontiers in Child and Neurodevelopmental Psychiatry finds that although “second-generation antipsychotics remain the mainstay of treatment … current medications provide suboptimal response at best.” The authors recommend, based on the adult literature, adding psychotherapeutic intervention for “a more comprehensive treatment strategy.”

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Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected].


  1. this is why the hearing voices approach is so important, it has freed many people from the tyranny of their voices and helped them gain control of their experience. Many having been able to come off anti -psychotics completely , whilst others have reduced their medication. As well as hearing voices groups, there is one-one work using tools like the working with voices workbook and the maastricht interview and voice dialoguing. This approach is beginning to take root in America but has been used for 25 years in the Uk and some other european countries. there are also growing networks in Australia and New Zealand

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