Antidepressants Associated with Preterm Birth, Infant Convulsions


A study of 228,876 pregnancies, published in the July issue of the American journal of Obstetrics & Gynecology, finds that maternal antidepressant use is associated with shortened (4-5 days) gestational age; for each prescription filled in the second trimester, the risk of early labor doubled.  In the third trimester, antidepressant use was associated with an elevated risk of infant convulsions.

Abstract → 

Hayes, R., Wu, P., et al; “Maternal antidepressant use and adverse outcomes: a cohort study of 228,876 pregnancies,American Journal of Obstetrics & Gynecology Vol. 207(1) 49.e`-49.e9, July 2012

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Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected].