Antidepressants Cause Autism-Like
Gene Expression in Fish


Prozac, Effexor, and/or carbamazepine induce gene expression patterns in the brains of fathead minnows that mimic those thought to be associated with autism in humans, according to a study published yesterday (June 6, 2012) in PLoS One. The study found that the pattern of gene expression was specific to idiopathic (heredity x environment) autism, but not other autism diagnoses associated with specific mutations. The authors write that the findings are consistent with a theorized role of elevated serotonergic neurodevelopmental perturbations during pregnancy that may be associated with a dramatic increase of idiopathic autism. Article →  Related Items: New Scientist: Antidepressants in Water Trigger Autism Genes in Fish The Telegraph: Autistic Fish: the Anatomy of a (Potential) Health Scare


Mad in America hosts blogs by a diverse group of writers. These posts are designed to serve as a public forum for a discussion—broadly speaking—of psychiatry and its treatments. The opinions expressed are the writers’ own.


Mad in America has made some changes to the commenting process. You no longer need to login or create an account on our site to comment. The only information needed is your name, email and comment text. Comments made with an account prior to this change will remain visible on the site.

Previous article“Psychiatric Power: A Personal View” by Pat Bracken
Next articleUS Senator Raises Concerns About Possible Stock Manipulation by Vertex Executives
Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected].