Researchers from Belgium and the Netherlands, publishing online June 20 in Neuroscience, found that prenatal fluoxetine (Prozac) differentially affected the development of glucocorticoid receptors in male (but not female) rats. This response to SSRI medications “may differentially alter the capacity of the hippocampus to respond to stress.”
Pawluski, J., Rayen, I, et al; “Developmental fluoxetine exposure differentially alters central and peripheral measures of the HPA system in adolescent male and female offspring,” Neuroscience, online June 20, 2012