Stress Sensitivity and Tolerance Associated With Psychosis


Researchers from Columbia and NYU found that stress sensitivity and impaired stress tolerance was greater in a cohort of 65 individuals deemed at high risk of psychosis, relative to controls. This tendency was associated over time with positive and negative symptoms, depression, anxiety and poor function. Life events were comparable in patients and controls, and was not associated with symptoms. Stress tolerance, symptoms, and function improved over time. Results appeared online June 1, 2012 in Psychological Medicine.

Abstract → 


Mad in America hosts blogs by a diverse group of writers. These posts are designed to serve as a public forum for a discussion—broadly speaking—of psychiatry and its treatments. The opinions expressed are the writers’ own.


Mad in America has made some changes to the commenting process. You no longer need to login or create an account on our site to comment. The only information needed is your name, email and comment text. Comments made with an account prior to this change will remain visible on the site.

Previous articlePremature Births Linked to Various Psychiatric Diagnoses
Next articleHeaven, Hell, and Psychosis
Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected].


  1. Oh look it’s ‘psychological medicine’s website, replete with shiny colorful photo of a neuron!

    The study? wow! People who are seeing a shrink are stressed out. People who volunteer to get paid to be the control group and are not ‘patients’ of a shrink are less stressed out. Whoopee!!

    Report comment

  2. i totally agree with this study in my case the delusion was like a product of impaired way of thinking that happened due to high stress all what i needed to do is to change or correct the way i use to process info (under stress) and i also agree with this part “Stress tolerance, symptoms, and function improved over time ” but i am sure that time is not the answer i mean psychologists must develop interventions to help us with the dysfunction and the emotional problems that accompany

    Report comment