Increased Risk of Heart Defects with SSRIs

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Danish research found a significantly increased risk of congenital heart defects in both the 4,183 pregnancies exposed to SSRIs throughout the first trimester and the 806 pregnancies for which SSRI use had been discontinued. The study acknowledges insufficient data to make conclusions about causality or possible confounding factors. The full study is available online from the British Medical Journal.

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Jimenez-Solem, E., Andersen, J., et al; “Exposure to selective serotonin reuptake inhibitors and the risk of congenital malformations: a nationwide cohort study.” BMJ Open, 2012;2:e001148

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Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected]