Trauma, First-Episode Schizophrenia, and Brain-Derived Neurotrophic Factor

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A team of Egyptian researchers found, in a sample of 74 outpatients, a relationship between trauma and first-episode schizophrenia, with a “mediating” role of brain-derived neurotrophic factor (BDNF). The study appears this month in the Journal of Nervous & Mental Disease.

Abstract →

Fawzi, M., Kira, I., et al; Trauma Profile in Egyptian Adolescents With First-Episode Schizophrenia: Relation to Psychopathology and Plasma Brain-Derived Neurotrophic Factor. Journal of Nervous & Mental Disease. January 2013

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Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected]