Researchers from the Mass General and Brigham & Women’s Hospitals and the Mt. Sinai School of Medicine find, using data from electronic health records of 38,397 adult patients with electrocardiograms recorded after prescription of antidepressant drugs or methadone between 1990 and 2011, a dose-response association between heath arrhythmias and Celexa, Elavil, and Lexapro.
Castro, V., Clements, C., Murphy, S., et al; QT interval and antidepressant use: a cross sectional study of electronic health records.
British Medical Journal. Online January 29, 2013
Of further interest:
Mass General EHR study probes antidepressant arrhythmia risks (Government Health IT)
Antidepressant link to heart changes confirmed (NHS Choices)
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at