Short “DUP” Predicts Better Outcome


A Hong Kong study links short “Duration of Untreated Psychosis” (DUP) to better long-term outcome.  The authors propose that factors linked to long DUP may be implicated in poor recovery, and so may provide targets for intervention.  Other than specifying that enrollees had taken antipsychotics for a week or less (1/2 being medication naive), treatment modality in this study was unspecified.

Abstract →

Tang, J., Chang, W., Hui, C., Wong, G., et al; Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: A first-episode psychosis study. Schizophrenia Research. Online February 11, .

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Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected].