“How Much Do We Know About Schizophrenia and How Well Do We Know It?”

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Research from Australia asks the question noted above, and answers “subtle, but diverse, structural brain alterations, altered electrophysiological functioning and sleep patterns, minor physical anomalies, neurological soft signs, and sensory alterations. There are markers of infection, inflammation or altered immunological parameters; and there is increased mortality from a range of causes. Risk for schizophrenia is increased with cannabis use, pregnancy and birth complications, prenatal exposure to Toxoplasma gondii, childhood central nervous system viral infections, childhood adversities, urbanicity and immigration (first and second generation), particularly in certain ethnic groups . . . We conclude that while our knowledge of schizophrenia is very substantial, our understanding of it remains limited.”

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