What the RADAR Trial Tells Us About Antipsychotic Reduction and Discontinuation

From Mad in the UK: The RADAR trial is complete. Disappointingly it showed that people who gradually reduce their antipsychotic medication are more likely to relapse than people who continue it. At 2-year follow-up there were no differences in social functioning, symptoms, side effects or quality of life. Yet relapse was far from inevitable and the qualitative analysis showed that some people felt empowered by the opportunity to reduce their medication with official support, regardless of the outcome.

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