KMSP News has aired a report of yet another mentally ill man pressured to enroll in a study of an unapproved antipsychotic drug, with near-disastrous results. His story bears a striking resemblance to the case of Dan Markingson, who committed suicide in a University of Minnesota study in 2004.
In 2004, a patient was given an experimental antipsychotic called bifeprunox and died of hepatorenal failure nine days later. But the sponsor apparently did not investigate the death for three years. In late 2007 the sponsor issued a safety alert and suspended all bifeprunox studies. This is where things get interesting.