Thursday, January 23, 2020

Committed at 16: Memories of a State Hospital

While most of the sting is gone, even now — almost sixty years on — I can’t get through a single day without thinking about shock treatment and the state hospital. I regularly have dreams or nightmares about being lost in a strange place and someone making me feel like dirt.

Mental Health Professionals and Patients Often Disagree on Causes of Symptoms

A new study finds that clinicians’ disregard for mental health patients’ insight into their own condition may be detrimental to treatment.
definition of relapse

What Does ‘Relapse’ Mean? Definitions Used in Antipsychotic Trials Are Unclear

Antipsychotic drugs are prescribed on the basis of trials that demonstrate a higher rate of ‘relapse’ in people who are withdrawn from these drugs compared to those who continue to take them. Yet, incredibly, there is no consensus about what ‘relapse’ means in this situation.

Researchers Address Dangers of Polypharmacy and Inappropriate Medication Use

A new special issue brings together articles exploring the harmful effects of simultaneous multiple medication use.
stoned or schizophrenia

From Stoned to “Schizophrenic”: My Mental Healthcare Journey

During a period of self-doubt, I chose to see a psychiatrist because I was engulfed in negative thoughts and couldn't find a direction in life. The slightest joys came only when I was high. Though my weed addiction was likely causing all of my symptoms, my psychiatrist’s response was to prescribe antipsychotics.

Relapse in Antipsychotic Drug Trials is Poorly Defined

There is a lack of consensus in the definition of ‘relapse’ across randomized controlled trials of antipsychotic maintenance treatment for schizophrenia and psychosis.

People Diagnosed with Bipolar Disorder at Increased Risk for Parkinson’s

Increased Parkinson's risk could be related to lithium, antipsychotic, and antiepileptic drug use.
long-acting medications pharmaceutical industry

A Guide to Long-Acting Neuroleptics: Education or Promotion?

The National Council for Behavioral Health has released a new pamphlet titled “Guide to Long-Acting Medications for Providers and Organizations.” By downplaying some aspects of the available science, the pamphlet implicitly acts as a promotional tool for the pharmaceutical industry.

Service-Users See Long-Term Antipsychotic Use as Compromising Recovery, Review Finds

A new meta-review examines the experiences of antipsychotic drugs use among people diagnosed with a psychotic disorder.

Sodium Nitroprusside Shows No Efficacy in Schizophrenia Treatment

Researchers question biases of preliminary trials that found that sodium nitroprusside, an antihypertensive drug, has positive effects on schizophrenia symptoms.

Withdrawal Symptoms Routinely Confound Findings of Psychiatric Drug Studies

Researchers examine how rapid discontinuation can mimic the relapse of mental health symptoms and confound psychiatric drug studies.

Psychiatrists View Drug-Free Programs for Psychosis as “Unscientific,” Study Finds

A new study provides an insider’s look into how psychiatrists view the establishment of drug-free programs in Norway.

Adderall Use Associated with Increased Risk of Psychosis

Twice as many teenagers with ADHD experienced severe psychosis when taking Adderall, as compared to Ritalin, according to a new study.

New Study Investigates Cannabidiol (CBD) for Psychosis

A new study examines the effects of CBD as an adjunct therapy to antipsychotic medication for patients diagnosed with schizophrenia.

Better Outcomes Off Medication for Those Recovered from First-Episode Schizophrenia

A new study has found that of 10 people who were fully recovered from their first episode of schizophrenia (FES), those not taking antipsychotics did better in terms of cognitive, social, and role functioning—and reached full recovery more quickly.

Antipsychotics Associated with High Risk of Death in Children

A new study has found that children and adolescents taking a high dose of antipsychotics are almost twice as likely to die of any cause than children on other types of medications.

Claims That Long-term Antipsychotic Use Leads to Better Outcomes are Misleading, Researchers Argue

Researchers reveal the limitations and misleading interpretations of two recent studies that claim to demonstrate that long-term antipsychotic use leads to better outcomes.

Researchers Warn of “Brain Atrophy” in Children Prescribed Antipsychotics

Researchers discuss the evidence that antipsychotic medications may cause brain atrophy in children, whose brains are still developing.

Gradual Tapering is Most Successful for Withdrawal from Antipsychotics

Mixed-Methods study explores the experiences of antipsychotic discontinuation among service users.
evidence base for neuroleptics

How Well Do Neuroleptics Work?

A recent paper published in Schizophrenia Bulletin reported on a meta-analysis of antipsychotic drugs which found that a significant number of people do not experience a remission of psychotic symptoms. The evidence base suggests that it is time for us to reappraise the effectiveness of these drugs and shift our practice patterns accordingly.

Two-Thirds of Schizophrenia Patients Do Not Remit on Antipsychotics

A new analysis of antipsychotic treatment of schizophrenia (published in Schizophrenia Bulletin) has found that two-thirds of patients treated this way do not experience symptom remission.

New Review of Antipsychotics for Schizophrenia Questions Evidence for Long Term Use

A systematic review of the limited research available on the long-term effects of antipsychotics finds fewer symptoms in those off of the drugs.

New Research on Patient-Centered Deprescribing for Antipsychotics

Researchers review the risks and benefits of deprescribing from antipsychotic drugs and advocate for a patient-centered approach to tapering.
antipsychotics survey

Did You Ever Stop Taking Antipsychotics? – World Survey on Withdrawal

Antipsychotics are big business, professionals are often at a loss as to how to help people going through disturbing experiences, the voices of patients are crowded out of the equation — there are many reasons for the lack of real education and informed consent around antipsychotics. To address this gap in knowledge, we launched a world study on antipsychotic medication withdrawal.

Call to Monitor Adverse Effects of Antipsychotics in Youth

Researchers point to the risks of using antipsychotics with youth and caution against the practice.

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