Tag: Genetics of bipolar disorder
Comments on Jeffrey Lieberman and Ogi Ogasâ Wall Street Journal Article...
The March 3rd, 2016 edition of the Wall Street Journal featured an article by past President of the American Psychiatric Association (APA) Jeffrey Lieberman and his colleague, computational neuroscientist Ogi Ogas. The article was entitled âGenetics and Mental IllnessâLetâs Not Get Carried Away.â In their piece, the authors started by expressing the belief that a recent study identified a gene that causes schizophrenia, and then discussed whether it is desirable or possible to remove allegedly pathological genes in the interest of creating a future âmentally perfect society.â The authors of the article, like many previous textbook authors, seem unfamiliar with the questionable âevidenceâ put forward by psychiatry as proof that its disorders are âhighly heritableâ In fact, DSM-5 Task Force Chair David Kupfer admitted that âweâre still waitingâ for the discovery of âbiological and genetic markersâ for psychiatric disorders.
Ernst RĂźdinâs Unpublished Family Study of âManic-Depressive Insanityâ and the Genetics...
Although it is axiomatic in psychiatry that genetic factors are involved in bipolar disorder (manic-depression), and that they play a predominant role, there currently exists little if any scientifically acceptable evidence that bipolar disorder and other âaffective disordersâ are caused by disordered genes. Given almost 50 years of gene discovery claims that were not confirmed by replication attempts, we must assume by default that current gene finding claims are false-positive results as well. In the 1920s, pioneering psychiatric geneticist Ernst RĂźdin decided against publishing his large family study of âmanic-depressive insanity,â most likely because the results did not fit his theories of Mendelian inheritance, and failed to support his advocacy of eugenic policies.