Tag: low efficacy of antidepressants

Despite ā€œFlurry of Interest,ā€ Ketamine Remains Unproven For Depression

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In 2014, then National Institute of Mental Health (NIMH) director, Thomas Insel, speculated that ketamine ā€œmight be the most important breakthrough in antidepressant treatment in decades.ā€ A recent review of the research suggests that while ketamine may produce a rapid short-term improvement in depression, the effect is short-lived and the potential for addiction and dependence warrants considerable caution.