Tag: randomized controlled trial

In adolescent depression treatment, those who received a placebo but thought they received Prozac improved more than those who received the drug and knew it.

This paper reviews the problems with the usual double-blind, placebo-controlled trials on which drug approvals are based, and advocates for a stricter form of testing psychiatric drugs with patient-relevant outcomes, real comparators, long-term outcomes, and assessment of harms.

A team in the Netherlands is currently investigating the effects of tapering off of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) during pregnancy....