Monday, October 3, 2022
Illustration of a shape of a baby crawling made out of various types of pills, on a black background

Health Risks to Babies When Antidepressants Used During Pregnancy

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Babies born to mothers taking antidepressants during pregnancy were more than six times as likely to have neonatal withdrawal syndrome—including breathing problems, irritability/agitation, tremors, feeding problems, and seizures—than those born to mothers taking other types of drugs.

Antidepressants No Better Than Placebo for About 85% of People

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Researchers can’t predict the 15% who benefit from antidepressants, and the other 85% are unnecessarily exposed to the harms of the drugs.

Less Than a Quarter of Those with Depression Respond to Treatment in Real Life

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In a real-world setting, less than a quarter of patients diagnosed with depression improved with medication, hospitalization, and therapy.
Man closely examing instructions on prescription medications

Antidepressant-Induced Serotonin Syndrome a Danger for the Elderly

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Researchers found that 25% of elderly patients taking antidepressants had serotonin syndrome, which is potentially life-threatening.

How to Distinguish Antidepressant Withdrawal from Relapse

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Mark Horowitz and David Taylor provide advice on how to tell the difference between antidepressant withdrawal and depression relapse.

Did Psychiatry Ever Endorse the Chemical Imbalance Theory of Depression?

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With the chemical imbalance theory falling out of fashion, researchers examine the claim that psychiatry never truly endorsed it.
Image of a young girl looking at a handful of antidepressants.

Antidepressants Do Not Improve Quality of Life

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A new study found that taking antidepressants did not improve quality of life.
Bored young man, staring out the train window on a rainy, grey and dull day

Patient Reports Reveal SSRI Antidepressants Often Lead to Emotional Blunting

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According to patient reports, SSRI antidepressants most frequently lead to the subjective experience of emotional blunting.
Girl, looking confused, holding pill bottle

Official Guidelines on Antidepressant Discontinuation Fail Practitioners and Patients

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A review of clinical practice guidelines for antidepressant discontinuation from across the English-speaking world reveals major pitfalls.
Depression related documents and drugs

Shifting Away from ECT and Antidepressants for Depression

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Researchers argue that we need a paradigm shift away from the biomedical model of mental illness to one informed by political action and common sense.

Negative Antidepressant Trials Still Unlikely to Be Published

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Antidepressant trials with negative results are still more likely than not to either be misleadingly spun as positive or unpublished.
Doctor attentively examines the MRI scan of the patient.

SSRI Antidepressants Do Not Improve Depression After a Stroke

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A study in JAMA Neurology finds that antidepressants do not reduce depression symptoms more than placebo in patients recovering from a stroke.
guy holding pill

New Review: Antidepressants Come with Minimal Benefits, Several Risks

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A review of research on antidepressant efficacy finds that an unfavorable risk-to-benefit ratio.

Overuse of Psychiatric Drugs is Worsening Public Mental Health, Doctor Argues

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A new research article asserts that the overuse of psychiatric drugs may create neurobiological changes that hamper long-term mental health recovery.

Researchers Push to End Placebo Run-in Periods in Antidepressant Studies

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Meta-analysis finds that the placebo run-in methodology reduces the placebo effect and finds antidepressants to be less useful.

Withdrawal Symptoms Cloud Findings of Antidepressant “Relapse” Trial

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Leading researchers point out that a new antidepressant study in NEJM failed to account for withdrawal symptoms, casting doubt on the results.

Giovanni Fava – A Different Psychiatry is Possible

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In this podcast, we hear from the renowned clinician and researcher Dr. Giovanni Fava about his latest book entitled “Discontinuing Antidepressant Medications”.

New Rating Tool for Tapering Antidepressants and Antipsychotics

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Researchers developed a rating scale to better assess service users’ experiences tapering antidepressant and/or antipsychotic medication.

Newborn Babies Go Through Antidepressant Withdrawal

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A new study finds that newborn babies experience antidepressant withdrawal after birth if their mothers take SSRIs when pregnant.

“Relapse” in Antidepressant Trials Likely Caused by Sudden Withdrawal

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A new study investigates how antidepressant withdrawal effects often get confounded with depression relapse in clinical trials.

Researchers Propose Study to Test Whether Antidepressants Impede Recovery

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Evolutionary theorists suggest that antidepressants interfere with the adaptive function of depression and propose a test of this theory.

Four Essential Studies on Antidepressant Withdrawal Every Prescriber Must Read

5
A researcher and service user Stevie Lewis recounts her own experience with antidepressant withdrawal and what she wishes her doctors knew.

No, the FDA’s Black Box Warning Did not Increase Suicides

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Researchers again debunk the claim that the FDA black box warnings on antidepressants led to more suicides.

Psychotherapy Can Prevent Relapse When Discontinuing Antidepressants

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“Short and simple psychological programs can prevent people from relapsing when they stop their antidepressants.”

Allen Frances Takes on the Over-Prescription of Antidepressants

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The prominent psychiatrist explores why antidepressants remain highly overprescribed and offers solutions to the problem.

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