Throughout the past two decades, studies have warned of increased suicide rates in those taking antidepressants, especially in children and adolescents. Researchers also documented...
People who take anticholinergic drugs, such as antidepressants and antipsychotics, are at a 50% higher risk of dementia.
Recent claims about antidepressant effectiveness have been based on misleading statements and misunderstandings of the science.
Researchers, publishing in Toxicology Research, review the evidence that antidepressant exposure in the womb is linked to autism spectrum disorders (ASD) in humans.
Researchers experimenting on mice found that exposure to fluoxetine (Prozac) in utero resulted in behaviors considered in animal studies to be analogous to autism in humans.
New study finds that antidepressants may negatively impact recovery after psychiatric hospitalization.
Dr. Vance Trudeau discusses his study's finding that antidepressants may have far-reaching, adverse effects that last up to three generations.
Study finds combining mirtazapine with an SSRI or SNRI is not clinically effective for improving depression in primary care patients who remained depressed after taking an SSRI or SNRI.
The researchers found that although antidepressants had a slight short-term effect on reducing the likelihood of depression diagnosis, there was no long-term improvement, nor any improvement in motor functioning.
Researchers question the overstated results of a large antidepressant meta-analysis and point to cultural pressures to turn to these drugs for a quick fix.
Biologists found that exposure to antidepressants suppresses important survival behaviors in zebrafish, an effect that persisted across three generations and was found to be more severe for males.
Researchers challenge the recommendation of starting two antidepressants simultaneously to increase preventative effects against suicide.
An international group of researchers, including several with financial ties to manufacturers of antidepressants, explore possible explanations for why long-term users of antidepressants become chronically depressed.
A new as-yet-unpublished trial of duloxetine (Cymbalta) for fibromyalgia has presented more evidence of suicidal events in teens.
Reanalysis of the original primary outcome measure in the STAR*D study suggests STAR*D findings inflate improvement on antidepressant medication and exclusion criteria in conventional clinical trials results in overestimation of antidepressant efficacy.
A new article in BMJ Evidence-Based Medicine addresses common misinterpretations of the efficacy research on antidepressants.
Alterations in gray matter and white matter development found in infants of mothers taking SSRI antidepressants during pregnancy.
During the past twenty years, the American Foundation for Suicide Prevention and American psychiatry have adopted a "medicalized" approach to preventing suicide, claiming that antidepressants are protective against suicide. Yet, the suicide rate in the United States has increased 30% since 2000, a time of rising usage of antidepressants. A review of studies of the effects of mental health treatment and antidepressants on suicide reveals why this medicalized approach has not only failed, but pushed suicide rates higher.
Researchers take action after study exposes enduring sexual dysfunction as a potential side effect of serotonin reuptake inhibiting antidepressants, 5α-reductase inhibitors, and isotretinoin.
A new study, published in Acta Psychiatrica Scandinavica, found that antidepressant efficacy was not dependent on severity.
Review of pediatric antidepressant studies finds the vast majority are negative on primary outcomes and an increased risk for suicidality.
Results from a Cochrane meta-analysis find that the common practice of prescribing antidepressants to treat insomnia is not supported by current evidence.
A systematic review of literature and meta-analysis indicates that there is no clinically or statistically significant effect of antidepressant dose increase after nonresponse to initial treatment.
Results from a 30-year prospective study demonstrated worse outcomes for people who took antidepressants, even after controlling for gender, education level, marriage, baseline severity, other affective disorders, suicidality, and family history of depression.
A new study published in Frontiers in Psychiatry concludes that “antidepressants are largely ineffective and potentially harmful.”