Antidepressants Linked to Heart Arrhythmias

February 2, 2013

Researchers from the Mass General and Brigham & Women’s Hospitals and the Mt. Sinai School of Medicine find, using data from electronic health records of 38,397 adult patients with electrocardiograms recorded after prescription of antidepressant drugs or methadone between 1990 and 2011, a dose-response association between heath arrhythmias and Celexa, Elavil, and Lexapro.

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Castro, V., Clements, C., Murphy, S., et al; QT interval and antidepressant use: a cross sectional study of electronic health records. British Medical Journal. Online January 29, 2013

Of further interest:
Mass General EHR study probes antidepressant arrhythmia risks (Government Health IT)
Antidepressant link to heart changes confirmed (NHS Choices)

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