Comparison of Two Five-Year Follow-up Studies.Bockoven, J. American Journal of Psychiatry, 132 (1975), 796-801.
In this study, Boston psychiatrists Sanbourne Bockoven and Harry Solomon compared relapse rates in the pre-drug era to those in the drug era, and found that patients in the pre-drug era had done better. Forty-five percent of the patients treated at Boston Psychopathic Hospital in 1947 had not relapsed in the five years following discharge, and 76% were successfully living in the community at the end of that follow-up period. In contrast, only 31% of patients treated in 1967 with drugs at a Boston community health center remained relapse-free for the next five years, and as a group they were much more “socially dependent”–on welfare, etc.–than those in the 1947 cohort.
Other researchers who reviewed relapse rates for New York psychiatric hospitals in the 1940s and early 1950s reported similar findings: roughly 50% of discharged schizophrenia patients had remained continuously well through lengthy follow-up periods, which was markedly superior to outcomes with neuroleptics. See Nathaniel Lehrman, “A state hospital population five years after admission: a yardstick for evaluative comparison of follow-up studies,” Psychiatric Quarterly, 34 (1960), 658-681; and H.L. Rachlin, “Follow-up study of 317 patients discharged from Hillside Hospital in 1950,” J. Hillside Hospital, 5 (1956), 17-40.
