Schizophrenia Prevents Cancer; Antipsychotics May Cause It


In a review of all 59,233 individuals diagnosed with schizophrenia in Sweden between 1965 and 2008, researchers from Sweden and the U.S. identified 6137 who developed cancer.  They found that familial/genetic factors contributing to schizophrenia may protect against cancer in those diagnosed with schizophrenia and their relatives, but that the increased risk of breast, cervical and endometrial cancers found after a schizophrenia diagnosis could be attributed to the use of antipsychotics. Results will appear in Schizophrenia Bulletin.

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Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected].


  1. Back in the 60s, Dr. Abram Hoffer noted that schizophrenics seldom get cancer. He found metabolites of epinephrine he called “adrenochrome” in the blood of of most patients diagnosed as schizophrenic. Adrenochrome is similar to mescaline, the drug which most closely produces the schizophrenic experience.

    Hoffer went on to enable thousands to recover from schizophrenia with orthomolecular therapy amd also enabled many cancer recoveries. In the 1990s, Abram Hoffer’s long-time associate John Smythies concluded that adrenochrome is protective against cancer and found that most schizophrenics lack the functioning gene for Gultathione S Transferese which detoxifies adrenochrome.

    In the 1930s, the Swedish ophthalmologist Henrik Sjogren noted particle deposits on the retinas of some of his patients who also had other symptoms in common, later called Sjogren’s Syndrome. Those particle deposits were later identified as adrenochrome. The offspring of mothers with Sjogren’s Syndrome are at increased risk for a later diagnosis of schizophrenia.

    In spite of these long-ago discoveries, biological psychiatrists still do not test the blood of their patients for adrenochrome when making a diagnosis of schizophrenia. I feel the reason for this is that adrenochrome levels can be lowered, and the symptoms of “schizophrenia” put into permanent remission with non-drug diet and dietary supplement therapy.

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    • You probably have that right. Nothing is more likely to raise our “biological” psychiatrists’ hackles than verification of Hoffer and Osmond’s adrenochrome hypothesis, as it was probably officially “refuted” by the prior generation’s “experts”. That the treatment the pair used didn’t involve patented “antipsychotic” drugs probably made it even less acceptable.

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