Human Behavioral Genetics’ “Unfulfilled Promise”

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A review of the literature on behavioral genetics, published online today by Developmental Psychobiology, finds “powerful new methods have failed to reveal even one bona fide, replicable gene effect pertinent to the normal range of variation in intelligence and personality. There is no explanatory or predictive value in that genetic information … Genetically, the disorders are heterogeneous; different cases with the same diagnosis have different causes. The promises of the molecular genetic revolution have not been fulfilled in behavioral domains of most interest to human psychology.”

Abstract → 

Wahlsten, D. “The hunt for gene effects pertinent to behavioral traits and psychiatric disorders: From mouse to human.” Developmental Psychobiology, online June 8, 2012

 

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Mad in America hosts blogs by a diverse group of writers. These posts are designed to serve as a public forum for a discussion—broadly speaking—of psychiatry and its treatments. The opinions expressed are the writers’ own.

2 COMMENTS

  1. See The Crumbling Pillars of Behavioral Genetics http://www.criticalpsychiatry.net/?p=624

    Improvements Are Needed for Accuracy in Gene-By-Environment Interaction Studies, Experts Say http://www.sciencedaily.com/releases/2011/09/110908124614.htm

    Study Says DNA’s Power to Predict Illness Is Limited http://www.nytimes.com/2012/04/03/health/research/dnas-power-to-predict-is-limited-study-finds.html

    The Limits of Genetic Testing http://www.theatlantic.com/health/archive/2012/04/the-limits-of-genetic-testing/255416/

    Genes Show Limited Value in Predicting Diseases http://www.nytimes.com/2009/04/16/health/research/16gene.html

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