Scientific American explores a crowdfunded approach to researching methamphetamine addiction, suggesting the approach is adaptable to pursuing other questions that are challenged to find sufficient scientific interest. “In spite of the legions of psychiatrists prescribing a record number of antidepressants and other medications every year, we still don’t have a good idea how these compounds work… In the current economy and funding environment, Small Science is likely to be consistent while Big Science happens in fits and starts.”