No Metabolic Risk for Antipsychotic-Naive Patients

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An Austrian study of the baseline prevalence of metabolic abnormalities and changes following treatment with five commonly-used antipsychotic drugs (haloperidol, amisulpride, olanzapine, quetiapine or ziprasidone) in first-episode, partially antipsychotic-naive patients with schizophrenia found that the overall prevalence was similar to the rate seen in both antipsychotic-naive patients and the general population. The study, published in the International Journal of Neuropsychopharmacology, found that metabolic risk increased significantly in all groups over the 52-week followup.

Abstract →

Fleischhacker WW, Siu CO, Bodén R, Pappadopulos E, Karayal ON, Kahn RS; Metabolic risk factors in first-episode schizophrenia: baseline prevalence and course analysed from the European First-Episode Schizophrenia Trial. International Journal of Neuropsychopharmacology. 2012 Dec 20:1-9. [Epub ahead of print]

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Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University as well as an MFT degree from the Council for Relationships in Philadelphia. Kermit leads workshops and webinars on the role of humor in psychotherapy and other human services. You can reach him at [email protected].

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