SSRIs Can Impair New Learning
About Anxiety

Kermit Cole
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136

Researchers from Columbia University and the New York State Psychiatric Institute test the behavioral effects of SSRIs on Pavlovian fear conditioning in rats, and propose a model by which acute SSRI administration alters neural activity in the amygdala and hippocampus in a way that reduces anxiety symptoms but impairs the ability to learn new responses anxiety. Results appear in this month’s Neuroscience.

Abstract →

Burghardt, N., Bauer, E.; Acute and Chronic Effects of SSRI Treatment on Fear Conditioning: Implications for Underlying Fear Circuits. Neuroscience. Online June 1, 2013

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Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected]

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