Sleep Sweeps Toxic Metabolites Out of the Brain

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Adding to our knowledge about the connection between sleep and mental health, researchers from the University of Rochester and N.Y.U. find that sleep creates the conditions for a greater exchange of cerebrospinal fluid with interstitial fluid in the brain, which in turn promotes increased removal of potentially neurotoxic waste products that accumulate during brain activity while awake.

Abstract →

Xie, L., Kang, H., Xu, Q., Chen, M., et al; Sleep Drives Metabolite Clearance from the Adult Brain. Science. 18 October 2013: 342(6156) 373-377. DOI: 10.1126/science.1241224

Of further interest:
Sleep Allows Brain to Wash out Junk (Science News)
Sleep: The Brain’s Housekeeper? (Science)
Sleep It Out (Science)

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Kermit Cole
Kermit Cole is a licensed marriage and family therapist based in Santa Fe, New Mexico. He and his partner, Luisa Putnam, joined by their mutual interest in working with trauma and psychosis, studied Open Dialogue in Finland and Peer-supported Open Dialogue in the UK in order to practice and teach as a team. In 2011, they joined with Robert Whitaker to found the Mad in America website

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