Increased Risk of Preterm Birth in Women Taking Antidepressants


A detailed meta-analysis of the published research on women taking antidepressants during pregnancy finds that the rate of preterm birth is nearly doubled in the third trimester.  In a comprehensive, systematic review the authors found that an overwhelming majority of studies (39 of the 41) showed increased rates of preterm birth in the antidepressant group, including when controlling for underlying depression.

Hubrechts, K., Sanghani, R., Avorn, J., Urato, A.; Preterm Birth and Antidepressant Medication Use during Pregnancy: A Systematic Review and Meta-Analysis. PLoS One. Online March 26, 2014. DOI: 10.1371/journal.pone.0092778

Antidepressants and Preterm Birth: More Concerning Findings by MIA blogger Adam Urato, MD (an author of the study)

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Kermit Cole
Kermit Cole, MFT, founding editor of Mad in America, works in Santa Fe, New Mexico as a couples and family therapist. Inspired by Open Dialogue, he works as part of a team and consults with couples and families that have members identified as patients. His work in residential treatment — largely with severely traumatized and/or "psychotic" clients — led to an appreciation of the power and beauty of systemic philosophy and practice, as the alternative to the prevailing focus on individual pathology. A former film-maker, he has undergraduate and master's degrees in psychology from Harvard University, as well as an MFT degree from the Council for Relationships in Philadelphia. He is a doctoral candidate with the Taos Institute and the Free University of Brussels. You can reach him at [email protected].


  1. A mother, who was thrown in jail and charged with endangering the welfare of a child after breastfeeding her baby while drinking, said she didn’t know she was possibly breaking the law.

    “I did drink. I did breastfeed,” Tasha Adams told ABC News’ “20/20” in her first on-camera interview. “I didn’t know it was illegal. If I knew it was illegal, I wouldn’t have done it.”

    Of course no one from these pharma companies ever goes to jail for endangering the welfare of children, ever.

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